Collins Street Specialist Centre (CSSC) is a premier multi-disciplinary dental specialist practice located in Melbourne's Central Business District. The centre provides comprehensive specialist dental care covering all six major fields of dental specialisation recognised by the Dental Board of Australia: Oral & Maxillofacial Surgery, Endodontics, Orthodontics, Periodontics, Prosthodontics, and Paediatric Dentistry.

The practice occupies heritage-restored premises within the iconic Manchester Unity Building at 220 Collins Street, a landmark Art Deco structure on the corner of Collins and Swanston Streets. With over 27 years of operation in Melbourne.